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Starfill: The Korean Filler Built on Ultra-Low Endotoxin Technology
Written by FillersFairy Editorial · Reviewed by FillersFairy Clinical Team · Last updated: July 5, 2026
Quick Answer
Starfill is a crosslinked HA dermal filler series by JETEMA (South Korea) manufactured using ZEEP (Zero Endotoxin and BDDE Entire Process) technology — a proprietary process that achieves ultra-low endotoxin levels (<0.05 EU/mL) and minimal residual BDDE (<0.5 ppm). The product line has three tiers: Plus (fine lines, 6–12 months), Deep Plus (moderate-to-deep wrinkles, 9–15 months), and Implant Plus (severe lines and volumisation, 12–18 months). All at 24 mg/mL HA with 0.3% lidocaine and CE certification. ZEEP's dual safety focus — controlling both endotoxin AND BDDE — distinguishes Starfill from fillers that address only one of these safety parameters.
What Is ZEEP Technology — Dual Safety Focus
Most HA filler manufacturers focus on minimising residual BDDE — the crosslinking agent that can cause inflammatory reactions if left unreacted in the gel. JETEMA went further with ZEEP by targeting both BDDE and endotoxins simultaneously.
Endotoxins are bacterial cell wall fragments that can trigger immune responses. They’re present in raw materials, water, and manufacturing equipment — and are extremely difficult to eliminate completely. Most HA fillers control endotoxins to “acceptable” levels. ZEEP technology pushes endotoxin levels to <0.05 EU/mL — well below the threshold that triggers measurable immune activation.
BDDE residue in Starfill is controlled to <0.5 ppm through the same ZEEP process — comparable to or better than the industry standard of 0.2–2 ppm.
The dual control is what makes ZEEP distinctive: low BDDE is common in premium fillers, but the combination of ultra-low BDDE plus ultra-low endotoxin in a single manufacturing process is rare. For clinics that want the strongest possible safety narrative, Starfill delivers on both parameters with documented test data.
The Three-Tier Product Line
| Product | Density | Best For | Injection Depth | Duration |
|---|---|---|---|---|
| StarFill Plus Lidocaine | Low | Fine superficial wrinkles: crow’s feet, forehead lines, perioral lines | Superficial to mid-dermis | 6–12 months |
| StarFill Deep Plus Lidocaine | Medium | Moderate-to-deep wrinkles: nasolabial folds, marionette lines, glabellar lines, lip contouring | Mid to deep dermis | 9–15 months |
| StarFill Implant Plus Lidocaine | High | Severe wrinkles, facial volumisation: cheeks, chin, jawline, temple hollowing | Deep subcutaneous / supraperiosteal | 12–18 months |
The tiering logic: Higher crosslinking degree = denser gel = deeper injection = longer duration. The three products cover the full range of dermal filler indications from surface refinement to deep structural volumisation.
Technical Specifications
| Parameter | All Starfill Products |
|---|---|
| Manufacturer | JETEMA Co., Ltd. (South Korea) |
| HA Concentration | 24 mg/mL, crosslinked, non-animal origin |
| Technology | ZEEP (Zero Endotoxin and BDDE Entire Process) |
| Lidocaine | 0.3% (3 mg/mL) |
| Endotoxin Level | <0.05 EU/mL |
| BDDE Residue | <0.5 ppm |
| Pack Size | 1 × 1.1 mL (Plus, Deep Plus) / 1 × 1 mL (Implant Plus) |
| Certification | CE marked |
Clinical Applications by Tier
| Indication | Plus | Deep Plus | Implant Plus |
|---|---|---|---|
| Crow’s feet | ✅ | — | — |
| Forehead lines | ✅ | — | — |
| Nasolabial folds | — | ✅ | ✅ |
| Marionette lines | — | ✅ | — |
| Lip contouring/augmentation | Border | ✅ Volume | — |
| Cheek volumisation | — | — | ✅ |
| Chin/jawline contouring | — | — | ✅ |
| Temple hollowing | — | — | ✅ |
Why Clinics Choose Starfill
Dual safety data. Most filler brands highlight low BDDE. Starfill highlights low BDDE AND low endotoxin — a stronger safety narrative for informed patients and for clinics operating in regulated markets.
Three-tier coverage. One manufacturer, one technology, three densities. Plus for surface work, Deep Plus for standard corrections, Implant Plus for deep volumisation. Stock all three and you cover every filler indication without switching brands.
Duration advantage. The Implant Plus tier offers 12–18 months of duration — comparable to or exceeding premium Western brands. Longer duration means fewer retreatments per patient per year, which patients value.
Korean wholesale economics. ZEEP-technology fillers at Korean wholesale pricing deliver the dual benefit of a premium safety narrative at a competitive product cost. The margin potential is strong across all three tiers. Check Starfill wholesale pricing →
Practitioner Confidence Summary
Starfill’s ZEEP technology delivers what safety-conscious clinics want: documented ultra-low endotoxin (<0.05 EU/mL) AND ultra-low BDDE (<0.5 ppm) in every vial. The three-tier product line covers the full range of filler indications with 6–18 months of duration depending on tier. For clinics sourcing Korean dermal fillers at wholesale, Starfill offers a premium safety profile at competitive pricing — the kind of combination that builds both clinical confidence and business margin.
Frequently Asked Questions
What is Starfill filler?
Starfill is a crosslinked HA dermal filler series by JETEMA (South Korea). Three products — Plus (fine), Deep Plus (medium), Implant Plus (deep) — all manufactured using ZEEP technology for ultra-low endotoxin and BDDE levels. 24 mg/mL HA with 0.3% lidocaine. CE certified.
How long does Starfill last?
Depends on tier. Plus: 6–12 months (fine lines). Deep Plus: 9–15 months (nasolabial folds, marionette lines). Implant Plus: 12–18 months (cheeks, chin, volumisation). Higher crosslinking = denser gel = longer duration.
What is ZEEP technology?
ZEEP stands for “Zero Endotoxin and BDDE Entire Process” — JETEMA’s proprietary manufacturing process that simultaneously minimises both endotoxin levels (<0.05 EU/mL) and residual BDDE (<0.5 ppm). Most manufacturers control one or the other; ZEEP controls both.
Is Starfill safe?
Starfill is CE certified with documented ultra-low endotoxin and BDDE levels. WSRS (Wrinkle Severity Rating Scale) clinical assessments at 8, 16 and 24 weeks confirmed efficacy with no critical adverse effects. As with all injectable fillers, treatment should be performed by trained practitioners only.
How does Starfill compare to other Korean fillers?
Starfill’s differentiator is dual safety: both endotoxin AND BDDE controlled to ultra-low levels via ZEEP. Other Korean fillers (Elasty uses PNET, Dermalax uses SHAPE) focus primarily on BDDE control. All offer comparable HA concentration (24 mg/mL) and clinical performance. The choice depends on which safety narrative your clinic prioritises.
Related Guides
Disclosure: FillersFairy is a wholesale supplier of Starfill dermal fillers. This article is for educational purposes only and does not constitute medical advice.
References
- JETEMA Co., Ltd. Starfill product specifications and ZEEP technology documentation.
- Cosmo Korea. StarFill Plus / Deep Plus / Implant Plus product listings. cosmo-korea.com.
- Fillers Korea. Starfill Implant Plus Lidocaine technical specifications. fillerskorea.com.
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