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Buyer comparison · Korean botulinum toxin type A
Does Nabota or Botulax Last Longer?
Neither Korean type A has a sourced duration win — buy on maker, drying form, and vial size, not a marketing month count.
No sourced winner
Duration is not the fork
3–6 months
Class window, both brands
Vacuum vs freeze-dried
The difference you can see
Units stay product-specific
Recalibrate when switching
01Quick Answer
Read this paragraph; it is the whole comparison in one breath.
Nabota from Daewoong and Botulax from Hugel are both Korean botulinum toxin type A. No sourced head-to-head trial shows one brand lasting longer. Both sit in the same class window of about 3–6 months. Choose on vacuum-dried versus freeze-dried form, pack sizes, and the Jeuveau / Letybo sister-brand map — not a distributor month count. Units are not interchangeable.
02If Duration Is a Tie, What Actually Differs?
The difference you can check on the bench is how the vial arrives, not a hidden extra month of effect.
The vial may appear nearly empty before reconstitution. That is the listed appearance of the process, not a missing dose and not a packaging error. Hold the sealed vial to the light at an angle if you need to see the faint film.
Train receiving staff before the first shipment.
Botulax · Hugel
Freeze-dried white plug
Current FillersFairy listing
Hugel’s current copy describes a visible white freeze-dried plug in the vial. That is the form most teams already know from other lyophilized Korean type A products. It is not proof of a wider field, a stronger unit, or a longer course.
What you see is the process — not a duration upgrade.
Park and colleagues (2021) record the same split in a methods table: Nabota as vacuum-dried prabotulinumtoxinA, Botulax as freeze-dried letibotulinumtoxinA. That paper is about potency-test methods. It is not a duration trial of the two SKUs you would order. Metox vs Nabota covers the vacuum-drying class in more detail; this page does not.
03Who Makes Nabota and Botulax — and Are They Jeuveau or Letybo?
The US names people type into Google are sister brands, not a stamp on the Korean wholesale vial.
Nabota
Daewoong Pharmaceutical Co., Ltd.
Republic of Korea · wild-type strain · Hi-Pure™
Current listings name a wild-type C. botulinum working strain and Daewoong’s Hi-Pure™ process with vacuum-drying. Hi-Pure is a manufacturer technology name. It is not a sourced duration score against Botulax.
Jeuveau (prabotulinumtoxinA-xvfs) is the US-labeled Daewoong-family product, marketed by Evolus, FDA-approved in 2019 for glabellar lines in adults. The Jeuveau prescribing information describes a vacuum-dried 100-unit vial. That label applies to Jeuveau. It does not turn a Korean Nabota carton into an FDA-labeled SKU.
Botulax
Hugel Pharma
Republic of Korea · CBFC26 · freeze-dried
Current listings name Hugel’s CBFC26 working strain and freeze-drying. For a Botulax-only identity page, see What Is Botulax? This URL stays on the duration decision.
Letybo (letibotulinumtoxinA-wlbg) is the US-labeled Hugel product, FDA-approved in 2024 for glabellar lines in adults. That label applies to Letybo. It does not make Korean Botulax “FDA Botulax.”
Watch out“Nabota is FDA-approved” and “Botulax is FDA-approved” are the usual shortcut. The accurate sentence is: the same manufacturers have US-labeled products (Jeuveau, Letybo). The vial on a Korean wholesale listing is a different labeled SKU. Clinics that must inject a US-labeled product buy Jeuveau or Letybo in that market — not this export carton.
04What Is Actually In Each Vial?
Same molecule class, same broad excipient story — albumin is not the duration fork.
Both current listings are botulinum toxin type A with human serum albumin as a stabiliser and sodium chloride as a tonicity adjuster, supplied as a single vial for reconstitution with sterile 0.9% saline. Both unopened listings specify refrigerated storage at 2–8 °C, protected from light, do not freeze. This article does not publish dilution volumes or injection maps. Follow the IFU in the box.
A 2018 formulation comparison by Frevert and colleagues measured several Asian type A products, including Botulax and Nabota, against Xeomin. In that paper’s composition table, both Botulax and Nabota are listed with 0.5 mg human serum albumin and 0.9 mg sodium chloride per 100-unit vial. Park’s 2021 methods table records the same excipient pair for both.
Don’t be sold on extra albuminSeller copy that says Botulax “adds 20% more HSA so it lasts 15–30 days longer” contradicts the published composition tables we can cite. Frevert’s protein-load rows are laboratory data from named batches — not a clinic duration ranking. Frevert’s appearance column lists Nabota as a lyophilizate, which conflicts with the current vacuum-dried listing and with Park. For physical form, follow the current pack.
Why units are not interchangeableThe Jeuveau and Letybo prescribing information both state that potency units are specific to the preparation and assay and cannot be converted across botulinum toxin products. Switching from onabotulinumtoxinA, from Jeuveau, or between Nabota and Botulax is a practitioner calibration against the product in hand — not a public conversion spreadsheet.
05Does Nabota or Botulax Last Longer?
No sourced comparison shows a reliable duration winner.
Type A effect is temporary. Clinical weakening fades as neuromuscular signaling recovers. That biology is class science. It does not prove that Nabota outlasts Botulax, or the reverse, on the SKUs in the cart. FillersFairy’s current Nabota and Botulax product pages do not print a manufacturer duration range we can quote as a labeled claim.
Class window
About 3–6 months for this type A field
Week 2
Peak smoothness often discussed here
~3 months
Jeuveau / Letybo retreatment floor (those labels)
12–16 weeks
Letybo AU product information, glabellar
Nabota
3–6 months (mainstream)
No labeled duration range on the current FillersFairy Nabota pages. Sister-SKU Jeuveau: retreatment no more frequently than every three months — that sentence belongs to Jeuveau, not a ranking of Korean Nabota against Botulax.
Botulax
3–6 months (mainstream)
Same honest band. Sister-SKU Letybo: US label uses the same three-month floor; Australian product information describes glabellar effect around 12–16 weeks. Those figures describe labeled Letybo, not “Botulax lasts longer.”
6–9 month sheets are marketing until a named study on this SKU appears.
Watch outA bigger vial is not a longer toxin. Botulax 300U holds more labeled units per container. It does not add months of effect compared with Botulax 100U. Nabota 200U is the same story on the Daewoong side.
For a Botulax-only duration spoke, see How long does Botulax last? For a Nabota-only timeline, see Nabota before and after. This page’s job is the or: do not pick the brand on a fake extra month. Those spokes should not be read as a license to copy public area-by-area dose charts into a buying article. The same honest 3–6 month band is the one we use on Toxta vs Hutox.
06Is Faster Onset the Same as Longer Duration?
No. Onset is when softening is first noticed. Duration is how long useful weakening holds.
Current Nabota and Botulax listings on FillersFairy do not publish a head-to-head onset trial. Class language for type A is days to first change, with peak smoothness often discussed around week two. That is not a license to promise “Nabota always shows on day 2” or “Botulax is slower so it lasts longer.”
Buying implicationSet review photography on a clinic schedule you already use. Do not stock a second brand only because a blog promised a 48-hour race.
07Which Pack Should the Clinic Stock?
Pack size is inventory, not potency theatre. Current FillersFairy listings checked September 2026 — confirm the live page; presentations can change.
| Brand | Listed presentations | Form on the current page |
|---|---|---|
| Nabota | 100U, 200U | Vacuum-dried |
| Botulax pack fork | 100U, 200U, 300U | Freeze-dried — 300U is unique in this pair |
200U is not “stronger Nabota” or “stronger Botulax.” It is more labeled units in the vial. Confirm pack and stock on the live product page the day you raise the PO.
08How Do You Check the Box on Arrival?
Write a check chain, not a screenshot guarantee.
- 1Name and maker match the PO: Nabota / Daewoong, or Botulax / Hugel — not a lookalike English export name from another house.
- 2Unit count on carton and vial match (100, 200, or Botulax 300).
- 3Physical form matches the listing: Nabota may look nearly empty; Botulax should show the freeze-dried plug. A plug in a vacuum-dried SKU, or a truly vacant freeze-dried SKU, is a receiving flag.
- 4Seal, lot, expiry match across carton and vial. Cold chain on the current listings is 2–8 °C, do not freeze.
- 5Channel. Professional wholesale, not a social-market split bottle. For class counterfeit patterns, see Fake Botox.
Not in this articleThis page does not teach mixing two brands in one face, “trial 20 units,” or injection depth in millimetres. Those belong in the IFU and the treating practitioner’s protocol.
09Full Comparison Table
Every dimension, side by side. The first row is the difference that matters most.
| Dimension | Nabota (Daewoong) | Botulax (Hugel) |
|---|---|---|
| Product form | Vacuum-dried — vial may look nearly empty | Freeze-dried — visible white plug |
| Class | Botulinum toxin type A | Botulinum toxin type A |
| Strain on current listing | Wild-type C. botulinum | CBFC26 |
| Named process | Hi-Pure™ + vacuum-drying | Freeze-drying |
| Packs on current listing | 100U, 200U | 100U, 200U, 300U |
| Excipients | HSA + NaCl; papers cite 0.5 mg HSA + 0.9 mg NaCl per 100U | Same pair in the same papers |
| US sister brand | Jeuveau (2019) — different labeled SKU | Letybo (2024) — different labeled SKU |
| Duration we will claim |
Class window ~3–6 months; no sourced winsellers invent weeks
|
Samesome claim 6–9
|
| Units | Not interchangeable | Not interchangeable |
| Best for | Vacuum-dried handling; Daewoong / Jeuveau maker story | Visible freeze-dried plug; Hugel line including 300U |
10Which Buyer Should Pick Which?
Your buying priority decides the pick — not a fake extra month.
Shortlist Nabota
If the team will be taught the vacuum-dried look
You want Daewoong’s 100U / 200U line and the Jeuveau maker-family story when patients ask about the US name. The Korean vial is still not FDA-labeled Jeuveau stock.
Shortlist Botulax
If you want a conventional freeze-dried plug
And, if the live listing still carries it, a 300U container. That is a pack fork, not a 6–9 month product.
| If your priority is… | Start with… | Limit |
|---|---|---|
| Two maker families and two forms | Stock both | Recalibrate units; do not mix from this article |
| A US-labeled vial for a US chair | Jeuveau or Letybo in that market | This wholesale page is not that SKU |
| A proven extra month versus the other brand | Neither | No sourced duration win |
The common answerMany practices stock both because the form and pack forks are real. Choose another route when you need a liquid ready-to-use toxin (Korean Botox Brands hub) or when the legal product in your chair must be the US label.
Who should not use this page: patients buying for self-injection; any buyer asking us to name a week-count winner; clinics that must inject Jeuveau or Letybo and were about to order the Korean carton as a substitute.
Next step: confirm the live Nabota 100U or Botulax 100U page, then the 200U / 300U sibling if pack size is the actual need.
11FAQ
Does Nabota last longer than Botulax?
No sourced head-to-head trial shows a reliable win either way. Both are Korean botulinum toxin type A. Clinic-typical duration sits in the same class window of about 3–6 months. Muscle, treatment interval, and how the practitioner plans the session move duration more than the brand name. Distributor claims of 6–9 months, or of extra albumin buying extra weeks, are marketing unless a named study on that SKU is produced.
How long do Nabota and Botulax usually last?
Plan on the class window of about 3–6 months, not a brand-specific week count from a marketplace blog. US labels for the sister products Jeuveau and Letybo set a retreatment floor of about three months; Letybo’s Australian product information describes glabellar effect around 12–16 weeks. Those figures describe labeled US/AU SKUs. They are consistent with a seasonal course. They are not a ranking of the Korean wholesale vials.
Is Nabota the same as Jeuveau?
They share a manufacturer family. Jeuveau is the US-labeled prabotulinumtoxinA-xvfs product (Evolus; FDA 2019). Korean Nabota on a wholesale listing is a different labeled SKU. Do not treat the Nabota carton as FDA-labeled Jeuveau stock. Vacuum-drying appears on both the Nabota listing and the Jeuveau description — that is a form clue, not a regulatory identity.
Is Botulax the same as Letybo?
Same pattern. Letybo is Hugel’s US-labeled letibotulinumtoxinA-wlbg product (FDA 2024). Botulax is the Korean-market / export brand on this catalogue. Freeze-dried presentation is the form clue. It is not permission to write “Botulax is FDA-approved” on the Korean box.
Are Nabota and Botulax units interchangeable?
No. Potency units are specific to each product’s assay. Jeuveau and Letybo prescribing information both state that units cannot be converted across botulinum toxin products. House practice is the same for Nabota and Botulax: the treating practitioner recalibrates rather than pasting another brand’s unit plan. This article does not publish a conversion table.
Why does the Nabota vial look empty?
Because the current listing is vacuum-dried. A thin film can sit on the glass and look like nothing is there. The listed dose is still in the vial until reconstitution. Botulax is freeze-dried and should show a white plug. If the form does not match the SKU you ordered, stop and check lot, seal, and supplier — do not assume “empty” means fake on a vacuum-dried pack, and do not assume a freeze-dried plug means a longer result.
Does the 300U vial last longer than 100U?
No. 300U is more labeled units in one container. Duration of effect is not a property of carton size. Choose 300U when the live Botulax listing and your inventory math need that pack. Choose 100U when you want a smaller single-vial stock unit. The same logic applies to Nabota 100U versus 200U.
Should a clinic stock both?
Yes, if you want two maker families, two drying forms, and Botulax’s 300U option beside Nabota’s 100U / 200U line. No, if you were only stocking the second brand to win a duration argument this article cannot support. If you stock both, keep reconstitution and dosing on each IFU. Do not invent a mixed-brand protocol from a blog.
RSources
- FillersFairy current product listings (checked 4 September 2026): Nabota 100U, Nabota 200U, Botulax 100U, Botulax 200U, Botulax 300U. Layer A: maker, form, strain, pack, storage. These pages do not publish a duration RCT.
- Park JY, et al. Practical Application of Novel Test Methods to Evaluate the Potency of Botulinum Toxin: A Comparison Analysis among Widely Used Products in Korea. Toxins. 2021;13(12):833. Layer B: vacuum-dried Nabota vs freeze-dried Botulax; 0.5 mg HSA + 0.9 mg NaCl per 100U in the methods table. Not a duration trial of either SKU.
- Frevert J, Ahn KY, Park MY, Sunga O. Comparison of botulinum neurotoxin type A formulations in Asia. Clinical, Cosmetic and Investigational Dermatology. 2018;11:327–331. PMC6039073. Layer B: both products listed with 0.5 mg HSA and 0.9 mg NaCl per 100U. Protein-load rows are not duration outcomes. Appearance column conflicts with the current Nabota vacuum-dried listing — form follows the live pack.
- Evolus / FDA. JEUVEAU (prabotulinumtoxinA-xvfs) prescribing information. Vacuum-dried 100-unit vial; units not interchangeable; retreatment no more frequently than every three months. Layer C for Jeuveau only.
- Hugel. LETYBO (letibotulinumtoxinA-wlbg) prescribing information. Units not interchangeable; retreatment no more frequently than every three months. Layer C for Letybo only.
- TGA. Letybo product information (AUSPAR attachment). Glabellar effect described as 12–16 weeks; intervals ≥12 weeks. Layer C for that labeled product, not Korean Botulax.
Evidence note: No Nabota-versus-Botulax randomised duration trial was used for this rewrite. Class physiology, sister-SKU labels, and two formulation papers are not a ranking of the Korean wholesale vials. Distributor month counts were treated as marketing.
Confirm pack, storage, and stock on the live product page before ordering. This article is buyer-side information for licensed professionals, not clinical guidance and not a mixing or dosing protocol. Administration follows a qualified practitioner and the manufacturer’s IFU. The buyer verifies legal import and use in their jurisdiction.
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