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Rejuran S 1.0ml
Polynucleotide (Scar Treatment) · PN (scar-grade concentration)
Quick Answer
Rejuran S is PharmaResearch's scar-treatment-specific polynucleotide — the Blue Box of the Rejuran family. It uses a higher-concentration PN formulation than Rejuran Healer, designed specifically for depressed atrophic scars including acne scarring, surgical scars, and early-stage stretch marks. Standard course is 3–5 sessions 3–4 weeks apart with focal subcision-style injection under each scar.
Last Reviewed
May 19, 2026
Manufacturer specification cross-verified
Treatment Protocol
3–5 sessions, 3–4 weeks apart. Maintenance as needed for treatment-resistant scars.
Why This Skinbooster Is Different
Rejuran S is the only product in the Rejuran range with KFDA approval specifically for scar treatment. The higher PN concentration drives more aggressive fibroblast activation and collagen synthesis in the scar bed — necessary because scar tissue has reduced cellular density and impaired regenerative response compared to normal dermis. Subcision-style focal bolus technique creates volume directly under the depression while triggering remodelling.
Mechanism of Action
High-Concentration PN for Depressed Scar Tissue Reconstruction. PN at scar-grade concentration is delivered via focal subcision-style injection directly beneath atrophic scar depressions. The needle insertion mechanically releases fibrous tethers binding the scar base; the deposited PN then triggers concentrated fibroblast activation in tissue that normally has impaired regenerative response. Over weeks, new collagen synthesis rebuilds dermal volume within the scar bed, gradually reducing visible depth.
Specifications
Clinical Indications
- Atrophic acne scars (icepick, rolling, boxcar)
- Post-surgical depressed scars
- Stretch marks (early-stage)
- Post-traumatic depressed scars
- Scar texture improvement and depth reduction
Compare Within Skinbooster Category
| Product | Active(s) | Mechanism | Protocol | Duration |
|---|---|---|---|---|
| Rejuran S 1.0ml | PN (scar-grade concentration) | High-Concentration PN for Depressed Scar Tissue Reconstruction | 3–5 sessions, 3–4 weeks apart. Maintenance as needed for treatment-resistant scars. | Cumulative scar improvement over the course; sustained 6+ months |
| Rejuran I 1ml | PN 2% (DOT™ Technology) | DOT™ Polynucleotide Fibroblast Activator (periocular) | 3 sessions, 3–4 weeks apart. Maintenance every 4 months. | 3–6 months after the initial 3-session course |
| Rejuran HB Hydro Booster | PN + HA + lidocaine | PN + HA Hybrid with Premixed Lidocaine (Hydro Booster) | 3 sessions, 3–4 weeks apart. Maintenance every 4–6 months. | 4–6 months sustained skin quality and hydration improvement |
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Frequently Asked Questions
Source verification:→ FDA 510(k) Database (verification)
Related Skin Boosters
Regulatory Notice. CE-marked Class III medical device. KFDA-approved for scar treatment. Manufactured by PharmaResearch under KGMP and ISO 13485. DOT™ Technology extraction. This product is manufactured outside the United States; FDA approval status is product-specific. For licensed healthcare professionals only. Practitioners are responsible for verifying regulatory status of this product in their jurisdiction before clinical use. Not for retail sale. Pricing subject to change.
Lisa Reynolds –
As a clinic owner, this is my second time buying Rejuran S from fillersfairy. Their prices are very attractive to me and it is hard to find genuine Rejuran S at such a big discount these days ,on average one box can save me $6.Rejuran S serum is a great way to meet the needs of customers for skin rejuvenation. My clients love the skin rejuvenation effects of Rejuran S. After completing the standard three-course treatment, problems such as scarring have been significantly improved are very satisfied with the changes in their skin.