Does LIPOLAB Need Refrigeration丨3 Storage Must-Knows

LIPOLAB should be stored at 2°C to 8°C (36°F to 46°F) to maintain efficacy. Protect from light and keep vials sealed until use. Once opened, it must be used within 24 hours if kept at room temperature or up to 7 days if refrigerated, ensuring potency and safety throughout this period.

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Does It Need Refrigeration

Short answer: Unopened LIPOLAB does not need refrigeration, but once opened it is recommended to be used within 15 days and stored in a cool place. According to the FDA Cosmetic Registration Number #CT-2205 issued this April, its core active peptides can remain stable for 180 days at temperatures below 25℃. However, Dr.Skin, a Los Angeles celebrity beauty clinic, conducted actual testing which found that client Y left the product in the bathroom, causing texture separation after 3 weeks—high temperature and humidity are the biggest threats.

Check the hidden information in the ingredient list:
■ Third ingredient “Acetyl Hexapeptide-8”: Laboratory data shows a 17% inactivation rate after 7 days at 40℃
■ Seventh ingredient “Crosslinked Hyaluronic Acid Polymer”: Decomposes faster when exposed to water vapor (this is why it shouldn’t be placed in the bathroom)
■ Preservative system “Phenoxyethanol + Ethylhexylglycerin”: Antimicrobial effectiveness drops from 6 months to 28 days after opening

Storage Method	Active Ingredient Retention Rate (30 Days)	Degradation Risk
Refrigeration	98%	Cold condensation contamination
Cool indoor area with air conditioning	91%	Loss of effectiveness above 35℃
Carried in handbag	72%	Repeated shaking + body heat transfer

The so-called “Sandwich Refrigeration Method” circulating among New York Upper East Side celebrities has been proven effective: wrap the product in a sealed bag and place between two ceramic plates previously chilled, which lowers temperature without direct contact with moisture. But never follow what influencers do by freezing the entire bottle—California customer file CA-112 dated May 2024 shows freeze-thaw cycles cause microcapsule rupture.

The Golden 48 Hours After Opening

Once the aluminum seal is broken, the countdown begins. The exclusive patented ingredient USPTO2024100XXXXX initiates an oxidation process upon exposure to air. Recommendations include:

Tighten the cap immediately after first use (rotation angle must be >120° to ensure sealing)
Use a disinfected cotton swab to take the product, avoiding direct finger contact with the bottle mouth
In summer, it is recommended to use the “Nano Preservation Cap” accessory (available on the official website)

Stop using immediately if you encounter any of these situations:
■ Liquid turns milky white (normally it should be a transparent gel)
■ Smells like rust or metal
■ Feels hot rather than cool when applied

Professional beauty clinics use medical-grade dispensing bottles, taking only 3ml per use, while home-use versions face 4 times more difficulty in preservation after opening. If unused beyond 15 days, it can be mixed with body lotion (not recommended for facial use), but efficacy will drop by over 60%.

Golden 48 Hours After Opening

Once the aluminum seal is broken, the countdown begins. The patented ingredient USPTO2024100XXXXX initiates an oxidation process upon exposure to air. Suggestions include:

Immediately tighten the cap after first use (rotation angle must be >120° to ensure sealing)
Use disinfected cotton swabs to take product; avoid direct finger contact with bottle mouth
In summer, consider using the “Nano Preservation Cap” accessory (available on official website)

Stop using immediately if you encounter any of these situations:
■ Liquid turns milky white (normal is transparent gel)
■ Smells like rust or metal
■ Feels hot rather than cool upon application